糖肾一号胶囊对早期糖尿病肾病患者血浆AngⅡ及GMP-140影响

Tangshen 1st Capsule Treatment Early Diabetic Nephropathy and Affect of Levels on Plasma AngⅡ and GMP-140

目的:观察糖肾一号胶囊对早期糖尿病肾病血浆血管紧张素(AngⅡ)及血小板α-颗粒膜蛋白(GMP-140)影响;方法:60例患者以就诊次序随机分为治疗组和对照组。对照组予以一般治疗,治疗组在对照组治疗基础上口服糖肾一号胶囊(生黄芪30 g,熟地黄12 g,山药15 g,山萸肉12 g,泽泻15 g,茯苓15 g,丹皮12 g,丹参20 g,芡实15 g,金樱子15 g),疗程12周。结果:治疗后治疗组血浆AngⅡ及GMP-140下降,与对照组比较有显著性差异(P<0.05)。结论:糖肾一号胶囊具有一定的延缓糖尿病肾病发展的作用。

Objective：To observe Tangshen 1st capsule treatment early diabetic nephropathy and affect of levels on plasma AngⅡ and GMP-140.Method：Sixty patients were randomly divided into two groups to the order of visits,treatment and control groups;control group were given general treatment;treatment group were treated based on the oral Tangshen 1st capsule（raw Huangqi 30 g,Shudi 12 g,Shanyao 15 g,Shanyurou 12 g,Zexie 15 g,Fuling 15 g,Danpi 12 g,Dansen 20 g,Qianshi 15 g,Jinyingzi 15 g）,12 weeks.Result：After treatment,the decreased levels of plasma Ang Ⅱ and GMP-140 compared with the control group there was significant difference（P 0.05）.Conclusion：Tangshen 1st capsule in delaing the development of diabetic nephropathy have certain effection.