红松松针化学成分的分离与鉴定

Isolation and identification of the chemical constituents from pine needle of Pinus koraiensis Sieb. et Zucc.

目的研究红松松针的化学成分,为松属植物的化学分类学研究提供依据。方法采用反复硅胶、聚酰胺、ODS、Sephadex LH-20柱色谱等方法进行分离纯化,根据理化性质和1H-NMR、13C-NMR等技术对分离得到的化合物进行结构鉴定。结果从红松松针中分离得到10个化合物,分别鉴定为epirhododendrin（1）、（＋）-rhododendrol（2）、覆盆子酮（frambinone,3）、massonianoside E（4）、松脂醇（pinoresinol,5）、罗汉松脂醇（matairesinol,6）、bornylp-coumarate（7）、salicifoliol（8）、β-谷甾醇（β-sitosterol,9）、胡萝卜苷（daucosterol,10）。结论化合物1和8为首次从松属植物中分离得到,2-7为首次从红松松针中分离得到。

Objective To study the chemical constituents of pine needles of Pinus koraiensis Sieb.et Zucc.Methods Compounds were isolated by the silica gel,ODS,Sephadex LH-20 column chromatography,and their structures were identified by their physicochemical properties and spectral analysis.Results Ten compounds were obtained and identified as epirhododendrin（1）,（＋）-rhododendrol（2）,frambinone（3）,massonianoside E（4）,pinoresinol（5）,matairesinol（6）,bornyl p-coumarate（7）,salicifoliol（8）,β-sitosterol（9）,daucosterol（10）.Conclusions Compounds 1 and 8 are obtained from Pinus for the first time.Compounds 27 are obtained from Pinus koraiensis Sieb.et Zucc.for the first time.