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Survivin基因与喉癌相关性

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摘要 喉癌的发生、发展受多种因素影响，其中凋亡抑制基因Survivin与喉癌的发生、发展、转移等有着密切的关系。本文就近年来Survivin的结构、功能及其与喉癌关系的研究进展做一综述。
作者 郝亚宁 骆文龙
机构地区 重庆医科大学附属第二医院耳鼻咽喉头颈外科
出处 《国际耳鼻咽喉头颈外科杂志》 2011年第1期17-19,共3页 International Journal of Otolaryngology-Head and Neck Surgery
关键词 喉肿瘤(Laryngeal Neoplasms) 凋亡抑制蛋白类(Inhibitor of Apoptosis Proteins)
分类号 R739.65 [医药卫生—肿瘤]
  • 相关文献

参考文献17

  • 1吕正华,栾信庸.喉癌临床治疗的辩证思维——浅谈当前临床医学为什么需要哲学[J].医学与哲学,2005,26(1):34-35. 被引量：9
  • 2Ambrosini G, Adida C, Altieri DC. A novel antiapoptosis gene, survivin, expressed in cancer and lymphoma. Nature Med, 1997, 3 (8) : 917-921.
  • 3sBang CI, Paik SY, Sun DI, et al. Cell growth inhibition and down-regulation of survivin by silibinin in a laryngeal squamous cell carcinoma cell line. Ann Otol Rhinol Laryngol, 2008, 117 (10) : 781-785.
  • 4Chen XM, Luan XY, Lei DP, et al. Suppression of survivin expression by short hairpin RNA induces apoptosis in human laryngeal carcinoma cells. ORL J Otorhinolaryngol Relat Spec, 2008, 70 (3) : 168-175.
  • 5Marioni G, Pillon M, Bertolin A, et al. The role of survivin expression in the differential diagnosis of laryngeal (glottic) verrucous squamous cell carcinoma. Eur J Surg Oncol, 2007, 33 (2) : 229-233.
  • 6Kanwar RK, Cheung CH, Chang JY, et al. Recent advances in anti-survivin treatments for cancer. Curr Med Chem, 2010, 17 (15) : 1509-1515.
  • 7Fortugno P, Wall NR, Giodini A, et al. Survivin exists in immunochemically distinct subcelluar Pools and is involved in spindle microtubule funcation. J Cell Sci, 2002, 115 (3) : 575-585.
  • 8王彦君,孔维佳,熊新高,张松,孙大为.Survivin和VEGF蛋白在喉癌组织中的表达及其相关性研究[J].临床耳鼻咽喉科杂志,2005,19(18):838-841. 被引量：10
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二级参考文献16

  • 1BRUGERE J, GUENEL P, LECLERC A, et al .Differential effects of tobacco and alcohol in cancer of the larynx, pharynx, and mouth[J].Cancer, 1986,57(2) :391 - 395.
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  • 3TUCHER H M,WOOD B G, LEVINE H, et al. Glottic reconstruction after near- total laryngectomy [ J ]. Laryngoscope, 1979,89:609 - 618.
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  • 6Ikehara M, Oshita F, Kameda Y, et al. Expression of survivin correlated with vessel invasion is a marker of poor prognosis in small adenocarcinoma of the lung. Oncol Rep, 2002, 9: 835-838.
  • 7Kennedy S M, O'Driscoll L, Purcell R, et al. Prognostic importance of survivin in breast cancer. Br J Cancer, 2003, 88: 1077-1083.
  • 8Kobayashi K,Hatano M,Otaki M,et al.Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation.Proc Natl Acad Sci USA, 1999,96: 1457-1462.
  • 9Shariat S F, Lotan Y, Saboorian H, et al. Survivin expression is associated with features of biologically aggressive prostate carcinoma. Cancer,2004,100: 751-757.
  • 10Miyachi K, Sasaki K, Onodera S, et al. Correlation between survivin mRNA expression and lymph node metastasis in gastric cancer. Gastric Cancer,2003, 6: 217-224.

共引文献16

国际耳鼻咽喉头颈外科杂志
2011年 第1期

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