咪达唑仑联合芬太尼静脉辅助硬膜外麻醉的临床观察

Clinical observation of midazolam combined fentanyl for epidural anesthesia

目的观察咪达唑仑、芬太尼在硬膜外阻滞手术中辅助用药的镇静效果及术后遗忘程度。方法选择手术患者120例,ASAⅠ～Ⅱ级,随机分为2组。A组为氟哌利多、芬太尼合剂组60例;B组为咪达唑仑、芬太尼合剂组60例。观察患者术前、术中、术后生命体征、镇静程度以及术后24 h顺行性遗忘程度和麻醉效果。结果 B组术中镇静程度、术后顺行性遗忘和麻醉效果明显优于A组。两组术前、术中、术后生命体征比较差异无统计学意义。结论咪达唑仑联合芬太尼作为硬膜外阻滞手术中的辅助用药,具有良好的镇静效果,不良反应轻,能够减少对手术的不良记忆和提高麻醉满意率。

Objective To observe the midazolam and fentanyl in epidural anesthesia adjunct to surgery and postoperative sedation forgotten observation.Methods 120 patients undergoing elective surgery,ASA Ⅰ-Ⅱ,were randomly divided into two groups.A group of droperidol,fentanyl mixture group 60 cases,B group of midazolam,fentanyl mixture group 60 cases were observed in patients with preoperative,intraoperative,and postoperative vital signs,sedation,24 hours after the degree of anterograde amnesia and anesthesia evaluation.Results Patients in B group in the level of sedation,anterograde amnesia after surgery and anesthesia were better than A group.Second,preoperative,intraoperative and postoperative vital signs were no significant differences.Conclusion Midazolam and Fentanyl epidural block as adjunct to surgery,has a good sedative effect,adverse reactions,to reduce the negative memories and to improve surgical anesthesia satisfaction rate.