不孕症实施腹腔镜下输卵管、卵巢电凝电切手术对卵巢功能的近期影响

Influence of laparoscopic electrocoagulation and resection of fallopian tube and ovary on ovarian function

目的:研究不孕症腹腔镜下实施输卵管、卵巢电凝、电切手术对卵巢功能的近期影响。方法:不孕症行腹腔镜下输卵管、卵巢电凝、电切手术53例,分别于术前(月经第2～3天),术后第1天、第5天、1个月(月经第2～3天)、3个月(月经第2～3天)抽血测定卵泡刺激素(FSH)、黄体生成素(LH)、催乳素(PRL)、雌二醇(E2)、孕酮(P)、睾酮(T)水平,术后随访6个月了解其排卵及妊娠情况。结果:53例不孕症患者术后第1天LH、E2、P、T水平增高(P<0.05);术后1个月除E2增高、LH下降(P<0.05);3个月PRL下降(P<0.05)。术后半年排卵率为92.45%,妊娠率为39.62%。结论:不孕症行腹腔镜下输卵管、卵巢电凝、电切手术不加重卵巢近期功能的损害。不孕症输卵管、卵巢手术后可提高排卵率及妊娠率。

Objective：To explore short-term influence of laparoscopic electrocoagulation and resection of fallopian tube and ovary on ovarian function.Methods：Serum levels of follicle stimulating hormone（FSH）,luteinizing hormone（LH）,prolactin（PRL）,estradiol（E2）,progesterone（P）,testosterone（T）of 53 infertile women were measured before the operation（2-3 days after menstruating）and on the first day,the fifth day,one month（2-3 days after menstruating）and three months（2-3 days after menstruating）after operations.They were followed up for six months to evaluate their ovulation rate and pregnancy rate.Results：Increased levels of LH,E2,P and T were found on the first day after operations（P0.05）.One month after operations,the level of E2 was increased while that of LH was decreased（P0.05）.Three months after the operations,the decreased level of PRL was found（P0.05）.Six months after the operations,the ovulation rate and pregnancy rate were 92.45% and 39.62% respectively.Conclusion：The laparoscopic electrocoagulation and resection would not aggravate the damage of the ovarian function in the short term.The surgery can improve both the ovulation rate and the pregnancy rate.