发作性运动诱发性运动障碍临床特征分析

Clinical Features of Paroxysmal Kinesigenic Dyskinesia

目的加深对发作性运动诱发性运动障碍(paroxysmal kinesigenic dyskinesia,PKD)的认识。方法对7例PKD患者的临床资料进行分析,总结PKD的临床特征和治疗方法。结果 7例患者均为散发病例,平均发病年龄约12岁。主要表现为运动启动时突然发生异常运动,发作时意识清楚,发作间期无神经系统阳性体征,发作频繁,持续时间<1 min;抗癫痫治疗有效。结论临床中应注意PKD与癫痫的鉴别,原发性PKD抗癫痫治疗有效,一般预后良好。

Objective To deepen the understanding of paroxysmal kinesigenic dyskinesia （PKD）. Methods Clinical data of 7 cases with PKD were analyzed to summarize the clinical feature and treatment of PKD. Results The average onset age of 7 sporadic cases was about 12 years old. They showed abnormal movement when starting to move. The seizure happened frequently with each time less than one minute. During the seizure, there was no nervous system positive sign, and patients had clear consciousness. Treatment for anti - epilepsy proved to be effective. Conclusion PKD and epilepsy should be differentiated at clinical work, and anti - epilepsy treatment of primary PKD proves to be effective with generally good prognosis.