食物性肉毒中毒患者的脑电图改变及其意义

The Changes and Significance of Electroencephalogram in the Alimentary Botulism

目的探讨食物性肉毒中毒患者脑电图(EEG)的变化及其意义。方法回顾性分析32例临床确诊为食物性肉毒中毒患者的EEG资料。结果 32例食物性肉毒中毒患者中有22例EEG异常,异常率为68.75%,主要表现为局限性或弥漫性慢波化、a波前移、背景活动呈低电压状态。不同程度食物性肉毒中毒患者EEG异常率间差异有统计学意义(P=0.025)。结论 EEG可作为食物性肉毒中毒的诊断手段之一,尤其在中度、重度中毒时;EEG可作为判断食物性肉毒中毒严重程度的指标;EEG的动态监测可判断食物性肉毒中毒的病情转归。

Objective To discuss the changes and significance of electroencephalogram in the alimentary botulism. Methods EEG data of 32 patients diagnosed with alimentary botulism were retrospectively analyzed. Results 22 among the 32 patients with alimentary botulism had abnormal EEG, the rate was 68.75%. The EEG abnormalities were characterized by the local or diffuse slow wave, a wave ante location, and low tension in the background activity. Conclusion EEG can be considered as one of the diagnostic instruments of the alimentary botulism, especially in the state of midrange and severe poisoning. EEG can be considered as valuable indicator to evaluate the severity of the alimentary botulism. EEG＇s dynamic monitoring can be considered as one of the indicators to judge the pathogen tic condition turnover of the alimentary botulism.