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同时伴有myc/IgH基因和bcl-2/IgH基因融合的B细胞淋巴瘤一例 被引量:1

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摘要 患者男,27岁。鼻塞8年余,持续性头痛2个月,伴双眼复视1个月。当地医院头颅CT考虑鼻咽癌侵犯蝶骨斜坡及蝶窦。2009年12月25日在本院磁共振成像(MR])检查考虑鼻咽癌侵犯中颅窝底骨质,并双侧咽后组、颈部Ⅱ区淋巴结转移。PET·CT检查符合淋巴瘤影像改变。实验室检查:乳酸脱氢酶(LDH)4.68μmol·s^-1·L^-1(正常值1.82~4.09μmol·s^-1·L^-1)。
出处 《中华病理学杂志》 CAS CSCD 北大核心 2011年第1期50-51,共2页 Chinese Journal of Pathology
基金 基金项目:广东省自然科学基金(06020908) 广东省人民医院科研基金(Y200521)
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参考文献5

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同被引文献18

  • 1Kanagal-Shamanna R, Medeiros W, Lu G, et al. High-grade B cell lymphoma, unclassifiable , with blastoid features: an unusual morphological subgroup associated frequently with BCU andl or MYC gene rearrangements and a poor prognosis. Histopathology, 2012,61 (5) :945-954.
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  • 8Johnson NA, Savage KJ, Ludkovski 0, et al. Lymphomas with concurrent BC[2 and MYC translocations , the critical factors associated with survival. Blood,2009, 114(11) :2273-2279.
  • 9Snuderl M, Kolman OK, Chen YB, et al. B-cell lymphomas with concurrent IgH-BCU and MYC rearrangements are aggressive neoplasms with clinical and pathologic features distinct from Burkitt lymphoma and diffuse large B-cell lymphoma. AmJ Surg Pathol ,2010 ,34 (3) :327 -340.
  • 10Li S, Lin P, Fayad LE, et al. B-cell lymphomas with MYC/8q24 rearrangements and IGH @ BCUlt ( 14; 18) ( q32; q21 ): an aggressive disease with heterogeneous histology, germinal center B-cell immunophenotype and poor outcome. Mod Pathol, 20 12 ,25 (1) : 145-156.

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