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CXCR4和CCR5在T淋巴细胞中的表达及与乳腺癌进展的相关性 被引量：2

Lymphocyte activation expression of its surface receptor CXCR4 and CCR5 in breast cancer patients
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摘要 乳腺癌发病率占妇女恶性肿瘤的第一位,且呈逐年上升趋势,乳腺癌远处转移缩短了患者的无病生存期,增加了病死率,也是目前临床治疗的难点.
作者 周立平 董西华 栾虹 李妍 姚凡 尚红
机构地区 中国医科大学附属第一医院检验科 中国医科大学附属第一医院肿瘤研究所 中国医科大学附属第一医院乳腺外科
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2011年第1期66-67,共2页 Chinese Journal of Laboratory Medicine
关键词 乳腺癌 T淋巴细胞 CXCR4 CCR5 相关性 无病生存期 恶性肿瘤 癌发病率
分类号 R737.9 [医药卫生—肿瘤]
  • 相关文献

参考文献8

  • 1Raman D,Baugher PJ,Thu YM,et al.Role of chemokines in tumor growth.Cancer Lett,2007,256:137-165.
  • 2Tanaka T,Bai Z,Srinoulprasert Y,et al.Chemokines in tumor progression and metastasis.Cancer Sci,2005,96:317-322.
  • 3Ishii I,Fukushima N,Ye X,et al.Lysophospholipid receptors:signaling and biology.Annu Rev Biochem,2004,73:321-354.
  • 4Balkwill F.The significance of cancer cell expression of the chemokine receptor CXCR4.Semin Cancer Biol,2004,14:171-179.
  • 5Pan J,Mestas J,Burdick MD,et al.Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis.Mol Cancer.2006,11:5-56.
  • 6Smith MC,Luker KE,Garbow JR,et al.CXCR4 regulates growth of both primary and metastatic breast cancer.Cancer Res,2004,64:8604-8612.
  • 7Kuss I,Hathway B,Ferris RL,et al.Decreased absolute counts of T lymphocyte subsets and their relation to disease in squamous cell carcinoma of the head and neck.Clin Cancer Res,2004,10:3775-3762.
  • 8Clinqan JM,Yanaqawa Y,Lwabuchi K,et al.Effect of T helper 1 (Th1)/Th2 cytokine on chemokine-induced dendritic cell functions.Cell Immunol,2006,242:72-79.

同被引文献20

  • 1Liekens S,Schols D,Hatse S.CXCL12-CXCR4 axis in angiogene-sis,metastasis and stem cell mobilization[J].Curr Pharm Des,2010,16(35):3903-3920.
  • 2Teicher BA,Fricker SP.CXCL12(SDF-1)/CXCR4 pathway incancer[J].Clin Cancer Res,2010,16(11):2927-2931.
  • 3Raman D,Baugher PJ,Thu YM,et al.Role of chemokines in tumorgrowth[J].Cancer Lett,2007,256(2):137-165.
  • 4Pils D,Pinter A,Reibenwein J,et al.In ovarian cancer the prog-nostic influence of HER2/neu is not dependent on the CXCR4/SDF-1 signalling pathway[J].Br J Cancer,2007,96(3):485-491.
  • 5Mashino K,Sadanaga N,Yamaguchi H,et al.Expression of chemo-kine receptor CCR7 is associated with lymph node metastasis ofgastric carcinoma[J].Cancer Res,2002,62(10):2937-2941.
  • 6Scotton C,Milliken D,Wilson J,et al.Analysis of CC chemokineand chemokine receptor expression in solid ovarian tumours[J].BrJ Cancer,2001,85(6):891-897.
  • 7Jordan NJ,Kolios G,Abbot SE,et al.Expression of functionalCXCR4 chemokine receptors on human colonic epithelial cells[J].J Clin Invest,1999,104(8):1061-1069.
  • 8Darash-Yahana M,Pikarsky E,Karplus R,et al.Role of highexpression levels of CXCR4 in tumor growth,vascularization,andmetastasis[J].FASEB J,2004,18(11):1240-1242.
  • 9Murakami T,Maki W,Cardones AR,et al.Expression of CXC chemo-kine receptor-4 enhances the pulmonary metastatic potential of murineB16 melanoma cells[J].Cancer Res,2002,62(24):7328-7334.
  • 10Zeelenberg IS,Ruuls-Van Stalle L,Roos E.Retention of CXCR4 inthe endoplasmic reticulum blocks dissemination of a T cell hybrido-ma[J].J Clin Invest,2001,108(2):269-277.

引证文献2

二级引证文献7

中华检验医学杂志
2011年 第1期

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