亚低温治疗重症脑梗死的疗效观察

Mild hypothermia treatment for severe cerebral infarction

目的 :探讨亚低温技术治疗重症脑梗死的临床效果。方法 :30例住院的重症脑梗死患者 ,分为治疗和对照两组 ,在给予抗脑梗死治疗的同时 ,治疗组加用亚低温技术 ,治疗后 7天、2 1天分别进行神经功能缺损评分 ,和病死率等一起进行分析。结果 :治疗 7天与 2 1天后 ,治疗和对照两组的评分分别为 30 .4 5± 5 .86 ,34.1 4± 5 .37( P=0 .0 5 ) ;和 2 1 .92± 2 .4 6 ,2 6 .82± 1 .99( P<0 .0 5 ) ;病死率分别为 2 0 %和 2 6 % ( P>0 .0 5 )。结论 :亚低温技术可以明显改善重症脑梗死患者的神经功能和预后。

Objective: To study the effect of mild hypothermia in the severe cerebral infarction (SCI). Methods: Thirty inpatients with SCI were selected; 15 cases as control and 15 cases treated by mild hypothermia (MHT, 32℃～34℃). Neurological deficiency score (NDS) was measured in the 7th day and 21th day after the treatment for two groups. Results: NDS was 32.45±5.86, and 34.14±5.37 from treated group and control group in the 7th day (P>0.05), respectively and 21.92±2.64, and 26.82±1.99 in the 21th day (P<0.05), reparately. Mortality was 20% (4/15) and 26% (4/15).Conclusion: MHT technology for the treated and control groups, could remarkably improve the neurological function and outcome of the patients with SCI, but not mortality rate.