无创呼吸机对慢性阻塞性肺疾病急性加重期合并2型糖尿病的疗效观察

Ciincal study of noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease incorporating with diabetes 2

目的 研究无创呼吸机对慢性阻塞性肺疾病急性加重期（AECOPD）合并2型糖尿病的患者的疗效观察.方法 将138例患者分为A1、A2和B三个组,每组46例,其中A1、A2组为AECOPD合并2型糖尿病患者,B组为无糖尿病的AECOPD患者.三组入院期间均给予常规治疗,三组同时用无创呼吸机治疗.结果 A2组和B组两组治疗前后血气分析和肺功能改善明显;A1组治疗前后动脉血氧分压无明显改善.经继续治疗后动脉血氧分压明显改善,但失败机会未改善.结论 对于AECOPD合并2型糖尿病的患者早期合理应用无创呼吸机对于血气分析及肺功能改善明显且使失败机会下降.

Objective To investigate the clinic effect of noninvasive ventilation（NIPV） on patients of acute exacerbation of chronic obstructive pulmonary （AECOPD） incorporating with diabetes 2. Methods The total of 138 patients were divided into 3 groups： AECOPD incorporating with diabetes 2 treating with NIPV：A1 group（46 cases）, A2 group（46 cases）,AECOPD group（46 cases）. The 3 groups were given noninvasive ventilation and the routine therapy. Results After intervention,the results of blood gas analysis and pulmonary functionin group A2 and group B are statistically different （ P 〈 0. 05） than before. The results of PaO2 in Group A1 are not statistically different than before. After intervention,PaO2is better than before in group Al, but the opportunity of failure is not improved. Conclusions Rational using the NIPV with AECOPD incorporating with diabetes 2 can improve blood gas analysis and pulmonary function, which decrease the opportunity of failure.