慢性阻塞性肺疾病诊治进展

Research progress on the diagnosis and treatment of chronic obstructive pulmonary disease

慢性阻塞性肺疾病（COPD）仍然是一个重要的公共卫生问题,也是病死率呈上升趋势的少数慢性疾病之一.近几年COPD发病机制、全身效应、急性发作和治疗等方面都有许多新的进展.目前COPD已被定义为可以预防、可以治疔的疾病,除了肺部病变的特点外,还伴有一些与患者疾病严重性相关的显著的肺外效应.本文从定义、诊断、病情评估和治疗等方面对COPD作一综述.

Chronic obstructive pulmonary disease （COPD） remains a major public health problem and is one of the few chronic diseases that have shown an increase in mortality. Recent years have seen important new information published on COPD, its pathogenesis, systemic effects, exacerbations, and treatment. Now, COPD is defined as a preventable and treatable disease with some significant extrapulmonary effects that may contribute to the severity in individual patients except for its characteristic pulmonary component. This article reviews the definition, diagnosis, staging classification and treatment of COPD.