骨的内分泌作用与中医肾主骨理论再探

Endocrine Actions of Bone and TCM Theory of Kidney Being in Charge of Bone

骨作为一个新揭示的内分泌器官,可分泌至少两种激素,对矿盐代谢和能量代谢产生重要调节作用,与骨质疏松、异位钙化、肾病、糖尿病、肥胖症等内分泌及代谢性疾病存在复杂关联。这些现代医学的新发现,与中医肾主骨藏精的传统理论不谋而合,折射出中医理论的科学超前性和经久不息的生命力。结合骨的内分泌作用研究,对中医肾主骨藏精理论进行了再思考,并展望某些作用于骨中药有可能通过调节骨内分泌而发挥全身作用,进而干预相关疾病。

Bone,as a newly uncovered endocrine organ,excretes at least two hormones,which regulate mineral and energy metabolism,thus keep complicated relations with a series of endocrine or metabolic disease,like osteoporosis,heterotopic calcification,nephrosis,diabetes,obesity,etc..These new discoveries in modern medicine quite meet the theory of kidney being in charge of bone in traditional Chinese medicine（TCM）,and that shows the scientific advance and vitality of the old TCM.In this paper,the endocrine actions of bone were revealed,and TCM theory of kidney being in charge of bone was restudied,and furthermore,that some Chinese medicinal herbs may treat certain disease via their actions on regulating bone endocrine,was prospected.