绝经后骨丢失的初步探讨及体重指数对骨密度的影响

Preliminary Study on Bone Lose in Post menopausal Women and Weight Index Effects on Bone Density

目的 探讨绝经后妇女不同年龄及不同绝经年限骨丢失的特点及体重指数对骨密度的影响。方法 对３６２ 例绝经后妇女（ 均为自然绝经） 分别超声测定右下肢胫骨中点骨密度。结果 ①绝经后骨密度在４５ ～５０ 岁时最高，５０ 岁以后随年龄的增长明显下降，７０ 岁以后趋于平稳。②骨密度在绝经后１ ～４ 年内下降幅度较小，５ ～７ 年下降幅度较大，７ ～１０ 年较平稳，１０～２０ 年再次下降，２０ 年以后下降幅度较小。③当体重指数＜ ３０ 时，骨密度随体重指数的增加而上升，＞ ３０ 时，骨密度下降。结论 绝经后妇女骨密度随年龄的增加而下降，与绝经年限呈非线性相关，呈两次下降，适当的体重对绝经后妇女的骨丢失有保护作用。

Objective To investigate the characteristics of bone loss and its relationship to age and menopause, and effect of weight index on bone density.Methods 362 postmenopausal women were enrolled. Bone density was measured in right tibia.Results Bone density of postmenopausal women were highest between 45 to 50 years old. After 50 years old, bone density decreased. Decrease of bone density were obsvious between 1 to 4 years and between 10 to 20 years after menopause. Bone density increased with weight index increasing when weight index<30. Bone densisy decreased when weight index>30. Conclusion Bone density of postmenopausal women increased with age, were nonlinear corrlative with duration of menopause. Appropriate weight prevent bone loss of postmenopausal women. [