摘要
目的观察兰索拉唑三联疗法对上消化道溃疡的临床疗效。方法将130例患者随机分为兰索拉唑治疗组(65例)、对照组(65例)。治疗组采用兰索拉唑30mg+左氧氟沙星0.2g+克拉霉素0.5g口服治疗,对照组采用法莫替丁20mg+左氧氟沙星0.2g+克拉霉素0.5g口服治疗,在治疗结束后观察临床症状改善情况并检测对Hp的根除情况。结果治疗组的总有效率及Hp根除率分别为93.85%和86.15%,明显的高于对照组81.54%和72.31%,两组相比均具有明显的统计学差异(P<0.05)。结论兰索拉唑三联疗法对上消化道溃疡具有较好的临床疗效,值得临床上推广使用。
Objective To explore the therapeutical effect of lansoprazole on gastroduodenal ucer. Methods 130 patients with gastroduodenal ucer were divided into treatment group （65 cases）and control group （65 cases） randomly. Patients in the treatment group were treated with lansoprazole ＋ levofloxacin ＋ clarithromycin. Patients in the control group were treated with famotidine ＋ levofloxacin ＋ clarithromycin. The symptoms and healing state were observed during and after treatment. Results The total curative rate and eradication rate of the treatment group were obviously better than that of the control group,and compared with the control group both of them have statistical difference （P〈0.05）. Conclusion The application of lansoprazole has a good clinical therapeutical effect on gastroduodenal ucer,and the it is worthy of being used wide range.
出处
《中国现代医生》
2011年第1期155-156,共2页
China Modern Doctor
