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脑梗死患者血清可溶性细胞间黏附分子-1和P-选择素水平变化的临床意义 被引量:2

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摘要 黏附分子在脑梗死后再灌注损伤的炎症反应中起重要作用。可溶性细胞间黏附分子-1(sICAM-1)主要由活化的血管内皮细胞表达,P-选择素在血小板和血管内皮细胞均有显著表达,他们介导了白细胞紧密黏附至血管内皮,进而迁移至内皮下空隙,加重了内皮损伤,参与缺血脑组织的炎性反应,加重脑组织损伤。我们检测了急性脑梗死患者sICAM-1和P-选择素水平变化,探讨其在脑梗死中的意义。
出处 《检验医学》 CAS 北大核心 2011年第1期31-31,35,共2页 Laboratory Medicine
基金 常州市卫生局指导性科技项目(WZ200915)
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