摘要急性妊娠脂肪肝（acute fatty of pregnavcy,AFLP）又称为妊娠急性肝萎缩,是妊娠期发生的一种严重的肝病,病死率高达85%以上,多见于初产妇及妊高症患者[1],大多发生于妊娠30-38周,与暴发性肝炎相似,通常先有消化道症状,数天后出现黄疸,以后黄疸逐渐加深,自然分娩一死胎后,
8Grimbert S,Fisch C,Deschamps D,et al.Effects of female sex hormones on mitochondria:possible role in acute fatty liver of pregnancy[J].Am J Physio1,1995,268(1):G107-G115.
9[1]Ching CL,Morgan M,Hainsworth I,et al.Prospective study of liver dysfunction in pregnancy in Southwest Wales[J].Gut,2002,51(6):876-880.
10[3]Sharhabeel MJ,wayyed MD,Face P,et al.An acute fatty liver of pregnaacy[J].The Journal of Emergency Medicine,1999,17(4):673-677.
5Goel A, Ramakrishna B, Zachariah U, et al. How accurate are the Swansca criteria to diagnose acute fatty liver of pregnancy in predicting hepatic mierovesieular steatosis? Gut, 2011,60 ( 1 ) : 138-139.
6Wei Q, Zhang L, Liu X. Clinical diagnosis and treatment of acute fatty liver of pregnancy: a literature review and 11 new cases. J Obstet Gynaecol Res,2010,36 (4) :751-756.
7Rakhejad Pevidece for acid oxidation in lum an planceta and the relation ship of fatty acid oxidation envyme ac-tivities with gestational age Placenta, 2002, 23 ( 50 ) : 447-450.
