色素放大肠镜与普通电子肠镜诊断结肠微小肿瘤性病变的价值比较

Comparison of diagnosis for colon minimal tumor lesions with pigment magnifying colonoscopy and normal electronic colonoscopy

目的比较普通电子结肠镜与色素放大内镜(FICE系统)对结肠粘膜微小肿瘤样病变的检出率,分析FICE系统在临床诊断中的使用价值。方法对2006年10月-2009年9月期间随机行普通电子结肠镜检查与FICE系统检查的结果进行回顾分析,以病理组织学诊断为标准,比较两种检查对微小肿瘤检出的灵敏度、特异度、阳性预测值和阴性预测值。结果剔除直径>5 mm肿瘤性病变患者,与病理组织学诊断比较,普通结肠镜诊断结肠粘膜诊断肿瘤性和非肿瘤性病变的灵敏度、特异度、阳性预测值和阴性预测值依次为68.0%、97.1%、78.0%和95.2%;FICE系统的灵敏度、特异度、阳性预测值和阴性预测值依次为87.9%、97.4%、89.9%和96.8%,其中灵敏度及阳性预测值显著高于普通结肠内镜检查结果 (P<0.05)。结论 FICE系统较普通电子结肠镜对结肠微小肿瘤的检出具有更加良好的临床应用价值。

Objective To compare the normal electronic colonoscopy and pigment magnifying colonoscopy（FICE system） on the detection rates for small tumor-like lesion of colonic mucosa,and analysis the value of pigment magnifying colonoscopy in the clinical diagnosis.Methods Retrospective analysis on the inspection results with normal electronic colonoscopy and normal electronic colonoscopy during October 2006 and September 2009 with random,and compare the two kinds of checks on positive rate and accuracy of detection for small tumors,pathology histological diagnosis as the standard.Results Excluding the patients with the tumor diameter exceed 5 mm and statistical analysis the detection rate of small tumors,normal electronic colonoscopy group was 3% and pigment magnifying colonoscopy group was 8%.Positive rate of pigment magnifying colonoscopy group was significantly higher than normal electronic colonoscopy group（P0.001）.Conclusion Detection rate of colon minimal tumor with pigment magnifying colonoscopy has improved significantly compare to normal electronic colonoscopy.