2型糖尿病合并冠心病危险因素分析

Risk factors of coronary heart disease in type 2 diabetes mellitus

目的分析2型糖尿病合并冠心病危险因素。方法应用多因素Logistic回归，分析了405例2型糖尿病患者有关冠心病的危险因素。结果①2型糖尿病病人冠心病发生率为26．2％；②年龄、糖尿病病程、高血压、体重指数、空腹血清C肽、甘油三酯、血清尿酸7个因素与Ⅱ型糖尿病病人冠心病发病有关。结论除了常见的冠心病危险因素外，为了防止2型糖尿病病人冠心病的发生，亦应注重控制高胰岛素血症、高甘油三酯血症和高尿酸血症。

Objective The relationship between coronary heart disease (CHD) and various risk factors were analysed. Methods 405 type 2 diabetic patients were analysed with multiple logistic regression. Results ① CHD incidence was 26. 2% in type 2 diabetic mellitus; ②Age, duration of DM, BMI,hypertension, fasting serum C-peptide,triglycerides and uric acid were correlated with CHD in type 2 diabetic patients. Conclusion Apart from conventional CHD risk factors,correction of hyperinsulinism,hypertriglyceridemia and high serum uric acid is crucial to prevent CHD in type 2 diabetic mellitus.