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102例晚期食管癌患者紫杉醇联合顺铂治疗观察 被引量:3

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摘要 目的观察紫杉醇(PTX)联合顺铂(DDP)组成的TP方案治疗晚期食管癌的近期疗效和毒副反应。方法 102例晚期食管癌患者,给予TP方案化疗:PTX 175 mg/m^2,静脉滴注,d1;DDP 40 mg/m^2,静脉滴注,d1~3,21 d为一个周期。结果 102例患者总有效率37.3%,稳定率54.9%,临床获益率达92.2%;毒副反应主要为剂量限制性毒性,表现为Ⅲ~Ⅳ度骨髓抑制(17.6%)。结论 TP方案治疗晚期食管癌有效率较高,毒副反应可耐受。
出处 《中国医学创新》 CAS 2011年第1期160-161,共2页 Medical Innovation of China
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