济南市区部分健康儿童麻疹抗体水平的检测

Detection of measles antibody level among healthy children in Jinan

【目的】了解济南市区儿童人群麻疹血清抗体水平,为制定预防对策提供依据。【方法】按照分层随机抽样的原则,对济南市儿童保健所的查体人群,按年龄分层随机抽取243人为调查对象,采样调查血清麻疹IgG抗体水平。【结果】总体麻疹抗体几何平均滴度(Geometric mean titer,GMT)为894,麻疹抗体阳性率为89.7%;不同性别麻疹抗体阳性率差异无统计学意义(P>0.05),女性抗体水平稍高(P<0.05);不同年龄间抗体GMT、阳性率、保护率差异均有统计学意义(P<0.01);有接种史人群麻疹抗体水平较无接种史人群高(P<0.01),有接种史人群麻疹阳性率及保护率均高于未接种人群(P<0.01),麻疹抗体GMT水平与接种次数无明显相关。【结论】人群麻疹血清抗体阳性率较高,短期麻疹流行可能性较小,但加强接种可以减少儿童感染麻疹的几率。

【Objective】 To know the measles antibody level among healthy children in urban field of Jinan,and to provide the evidence for working out measles control strategy. 【Method】 With cluster sampling,stratified sampling,and random sampling surveys,243 individuals were selected by age-stratified sampling in urban field,and their serum antibody levels were detected. 【Results】 The results showed that the positive rate of measles antibody was 89.7%,GMT was 894.No statistically significant difference was found in the positive rate of measles antibody between sex（P0.05）,female had higher measles antibody level（P0.05）;statistically significant difference was found in the positive rate of measles antibody,GMT and protection rate among age（P0.01）;statistically significant difference was found in the positive rate of measles antibody,GMT and protection rate between inoculation history（P0.01）,No statistically significant difference was found in GMT between inoculation times（P0.05）. 【Conclusion】 The measles antibody level is high among healthy population of JINAN City,so measles outbreak will be little chance in recent years,but vaccinum inoculation can degrade catching measles.