阿魏酸松柏酯的研究进展

Advances in Research of on Coniferyl Ferulate

阿魏酸松柏酯广泛存在于多种植物中,具有良好的药理活性,目前国内外对阿魏酸松柏酯的研究报道较少。该文通过查阅国内外近30年有关阿魏酸松柏酯的研究文献,对其理化性质、提取分离、含量测定、稳定性、生物活性等进行了系统综述。结果发现阿魏酸松柏酯性质很不稳定,在光照和高温下极易分解为阿魏酸,因此目前提取分离方法以加压液体萃取法为佳,高效液相色谱法仍为其含量测定的常用方法,其药理活性包括抗菌、抗肿瘤、抗氧化、舒张血管等。这些研究将为含阿魏酸松柏酯中药的质量标准制定及产品开发提供参考。

Coniferyl ferulate was widely present in various plants. In recent years, many studies were reported on it. However, more and more attention was paid to its excellent pharmacological activities discovered. In order to research it more systematically, the related reports during the past three decades years had been searched and summarized, including its physical and chemical properties, extraction and separation, content determination, stability and biological activities. Many studies showed that coniferyl ferulate is poorly unstable and easy to decompose, especially in the condition of strong light and high temperature, and so far the pressurized liquid extraction method was a better way to extract and high performance liquid was the method common used to content determination; Many of the strong pharmaceutical activities such as antimicrobial, anticancer, antioxidant, diastolic blood vessels were found, which provide information reference to quality standards and product development of chinese medicine containing Coniferyl ferulate.