摘要
目的比较度洛西汀和帕罗西汀治疗门诊抑郁症的疗效和副反应。方法 将符合CCMD-3抑郁症诊断标准的患者随机分为两组,分别给予度洛西汀及帕罗西汀治疗,治疗时间为6周,使用汉密尔顿抑郁量表(HAMD)、临床总体印象量表(CGI)、不良反应症状量表(TESS)进行评分。结果 两组有效率分别为80%和87%,在疗效和副反应方面两组差异无显著性。结论 度洛西汀是一种疗效好而安全的抗抑郁药,适用于门诊抑郁症患者。
Objective To compare clinical efficacy and side effects between Duloxetine and paroxetine in the treatment of depression in outpatients. Methods 62 patients who met CCMD - 2 - R for de - pression were randomly assigned to 2 groups. One group was treated with Duloxetine and the otherwith paroxetine for six weeks. Hamilton rating scale （HAMD）, clinical global impression scale （CGI）, and treatment emergent symptom scale （TESS） were used to assess. Results Total clinical effectiverate was 80% for Duloxetine group and 87% for paroxetine group. There were no differences in clinicaleffects and adverse reactions between the two groups. Conclusion The results indicate that Duloxetine is a safe and effective drug for the treatment of depression in outpatients.
出处
《中外医学研究》
2011年第1期16-17,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
