期刊文献+

氧驱动雾化吸入布地奈德治疗小儿急性喉炎效果观察 被引量:3

下载PDF
导出
摘要 目的了解氧驱动雾化吸入布地奈德治疗小儿急性喉炎效果。方法选择2008年7月~2009年12月在我院儿科门诊诊治的急性喉炎患儿共76例,治疗组(32例)采用氧驱动雾化吸入布地奈德混悬液,对照组(44例)采用地塞米松静脉滴注。所有病例均采用抗病毒、抗生素、退热药、化痰止咳等综合性治疗措施。结果显示治疗组的总有效率明显优于对照组,尤其是用药前24h和48h其差异均有统计学意义(P〈0.01)。结论氧驱动雾化吸入布地奈德治疗小儿急性喉炎(轻中度患者).方法简单,抗炎作用强。疗效确切。可避免或减少全身使用糖皮质激素,值得临床推广应用。
作者 方潜
出处 《海峡药学》 2011年第1期75-76,共2页 Strait Pharmaceutical Journal
  • 相关文献

参考文献5

二级参考文献30

  • 1李明华 殷凯生 等.哮喘病学[M].北京:人民卫生出版社,1999.570.
  • 2Skoner DP. Balancing safety and efficacy in pediatric asthma management. Pediatrics, 2002, 109:381-392.
  • 3Brutsche MH, Brutsche IC, Munawar M, et al. Comparison of pharmacokinetics and systemic effects of inhaled fluticasone propionate in patients with asthma and healthy volunteers: a randomized crossover study. Lancet, 2000, 356:556-561.
  • 4Heyder J. Deposition of inhaled particles in the human respiratory tract and consequences for regional targeting in respiratory drug delivery. Proc Am Thorac Soc, 2004,1:315-320.
  • 5Thorsson L, Edsbacker S, Kallen A, et al. Pharmacokinetics and systemic activity of fluticasone via Diskus and pMDI, and of budesonide via Turbuhaler. Br J Clin Pharmacol, 2001,52:529- 538.
  • 6Thorsson L, Edsbacker S, Conradson T-B. Lung deposition of budesonide from Turbnhaler is twice that from a pressurized metered-dose inhaler p-MDI. Eur Respir J, 1994, 7 : 1839-1844.
  • 7Kelly HW. Potential adverse effects of the inhaled corticosteroids. Jallergy Clin Immunol, 2003,112:469-478.
  • 8GINA executive committee. Global strategy for asthma management and prevention 2006. http://www, ginasthma, org/download, asp? intld = 217.
  • 9Kelly HW. Pharmaceutical characteristics that influence the clinical efficacy of inhaled corticosteroids. Ann Allergy Asthma Immunol, 2003, 91:326-334.
  • 10Agertoft L, Pedersen S. Short-term knemometry and urine cortisol excretion in children treated with flutieasone propionate and budesonide: a dose response study. Eur Respir J, 1997,10:1507- 1512.

共引文献2660

同被引文献17

引证文献3

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部