双黄连粉针合尼可林治疗脑卒中疗效观察

Observations on curative effects of Shuanghuanglian Injection(双黄连粉针) combined with nicholin on cerebral apoplexy

目的：观察双黄连粉针合用尼可林治疗脑卒中的疗效。方法：１９７ 例脑卒中患者随机分为治疗组１４７例和对照组５０ 例，治疗组采用双黄连粉针３６ ｇ／ｄ 合尼可林０７５ ｇ／ｄ 静滴，对照组用尼可林０７５ ｇ／ｄ 静滴，２组其他常规治疗相同。结果：治疗组总有效率９３９％ ，对照组总有效率为８２０％ ，２ 组比较有显著性差异（χ２＝６３４，Ｐ＜ ００５）。治疗组患者的血液流变学指标较对照组有更为明显的改善，发热患者的退热时间也明显缩短（χ２＝ １１７１，Ｐ＜ ０００５）。结论：双黄连粉针合尼可林治疗脑卒中疗效显著，且可明显改善患者的血液流变学指标，缩短发热患者的退热时间，值得临床推广。

Objective:To observe the curative effects of Shuanghuanglian Injection (SHLI,双黄连粉针) combined with nicholin on cerebral apoplexy(CA).Methods:197 cases with CA were divided into treatment group ( n =147) and control gorup ( n =50).The treatment group was treated with SHLI 3 6 g/day combined with nicholin 0 75 g/day infused intravenously meanwhile the control group treated with nicholin 0 75 g/day.The other therapy was same for two groups.Results:The total effective rate in treatment group was 93 9% but it was 82 0% in control group.In comparison between two groups the difference was significant (χ 2=6 34, P <0 05).The improvements of rheologic parameters in treatment group were more obvious than those in control group otherwise the durations for allaying fever significantly shorter than those in cotrol group (χ 2=11 71, P <0 005).Conclusions:The curative effects of SHLI combined with nicholin on CA are marked.It is able to improve the rheologic parameters of patients and to shorten the time of allaying fever in patients with fever.