烧烤食品和啤酒对大鼠肝脏抗氧化系统的影响

Effect of Barbecue Food and Beer on the Antioxidant System of Rat Liver

[目的]为促进人们科学饮食提供参考。[方法]用烧烤食品和啤酒喂养大鼠,以非烧烤食品和纯净水喂养的大鼠为对照组,利用分光光度法对烧烤食品和啤酒对大鼠肝脏超氧化物歧化酶(SOD)活性、过氧化氢酶(CAT)活性、清除·OH自由基能力、还原力及丙二醛(MDA)含量影响进行分析。[结果]烧烤食品和啤酒会降低大鼠肝脏抗氧化能力,其中SOD活性极显著降低,CAT活性显著降低,清除·OH自由基能力和还原力减弱,但与对照差异不显著,MDA含量极显著增加。[结论]大量食用烧烤食品和啤酒会使肝脏抗氧化能力减弱,氧化性损伤增加,因此应适当减少食用烧烤和啤酒,同时补充一些天然抗氧化剂有益于健康。

[Objective] The reference of the scientific diet for human body health was provided through the experiment..[Method] The rats were fed with barbecue（BBQ） food and beer and another group as CK was fed with non-BBQ food and pure water.The activity of superoxide dismutase（SOD）,the activity of catalase（CAT）,the ability of ·OH radical-removing,the reducing power and the content of malondialdehyde（MDA） in rat liver were measured by the spectrophotometric method and the data was analyzed.[Result] The BBQ food and beer would resulted in the reduction of the capacity of antioxidant of liver,particularly for significant decrement in the activity of SOD and CAT,and the ability in the ·OH radical-scavenging and reducing power was also decreased,which were not significantly difference with those of CK,and the content of MDA was significantly increased.[Conclusion] A diet of lots of BBQ food and beer would decrease the capacity of antioxidant of liver.Therefore the barbecue food and beer in diet should be appropriately reduced and the addition of some natural antioxidant food was beneficial to the health of human body.