猪附红细胞体病治疗试验

Treatment Experiment of Swine Eperythrozoonosis

[目的]探讨猪附红细胞体病主要特征及治疗方法,为该病防治提供参考依据。[方法]共分为3个试验组和1个对照组,猪舍之间完全隔开,30头/组,对发病和对照组红细胞进行镜检,并进行胆红素代谢试验以及三氮脒和强力霉素治疗对比试验。[结果]发病猪红细胞周围呈刺状或无规则形状,可不规则移动,在血浆中可见到游离活附红细胞体。治疗后,血浆中游离的附红细胞体消失。发病猪血清TBIL和IBIL明显升高,治疗后,治疗组和对照组有显著差异(P<0.05),三氮脒组和强力霉素组之间TBIL存在显著差异(P<0.05),并且强力霉素组IBIL降低至正常范围内(3.51μmol/L)。[结论]附红细胞体病可引起发病猪只IBIL显著升高,临床上使用三氮脒或强力霉素均有较好的治疗效果。

[Objective] To investigate the main features of swine eperythrozoonosis and treatment and provide a reference for prevention and control of swine eperythrozoonosis.[Method] All the swine were divided into three experimental groups and one control group,30 head/group.Microscopic examination of red blood cells,bilirubin metabolism test and diminazene and doxycycline treatment were performed,successively.[Result] The red blood cells of affected swine were around the spiny or irregular shapes,and showed irregular movement Free live Eperythrozoon could be seen in the plasma.After treatment,free Eperythrozoon disappear.TBIL and IBIL of affected swine significantly increased after treatment,the treatment group and control group were significantly different（P0.05）,and TBIL of diminazene group were significantly different with that of doxycycline group（P0.05）.Meanwhile,the IBIL reduced to the normal range（3.51 μmol/L） in doxycycline group.[Conclusion] Swine eperythrozoonosis can cause IBIL significantly higher.Doxycycline and diminazene have a better therapeutic effect.