摘要
目的探讨头颈部软骨肉瘤的临床表现、病理特点、鉴别诊断、治疗及预后。方法回顾分析我院自1997～2009收治的16例头颈部软骨肉瘤的临床资料,并对其进行随访。结果头颈部软骨肉瘤好发于鼻腔鼻窦、颞骨、下颌骨、上颌骨,以鼻腔鼻窦最常见,临床主要表现为牙齿麻木、变色、鼻部症状、面瘫、听力改变、张口受限等。头颈部软骨肉瘤以原发性中央型软骨肉瘤为主,诊断主要靠病理,治疗以手术根治性切除为主,随访显示头颈部软骨肉瘤主要死亡原因为肿瘤侵入颅内。结论头颈部软骨肉瘤是一种以局部侵袭为主的恶性肿瘤,应强调首次行根治性手术,并辅以增敏放疗。
Objective To investigate the clinical manifestation,pathological characteristics,differential diagnosis,therapy and prognosis of head and neck chondrosarcoma.Methods Sixteen cases of head and neck chondrosarcoma treated in our hospital from 1997 to 2009 were reviewed and analyzed.Results Head and neck chondrosarcoma occurred frequently in paranasal sinus and nasal cavity,temporal bone,mandible and maxilla.The clinical manifestations were teeth numbness,teeth discoloration,nosal symptoms,facial palsy,hearing change and limitation of mouth opening etc.Follow-up showed that the main cause of death was intracranial invasion.Conclusion Head and neck chondrosarcoma was an aggressive malignant tumor.Radical operation should be performed followed by sensitive radiotherapy.
出处
《北京口腔医学》
CAS
2010年第6期335-337,共3页
Beijing Journal of Stomatology
关键词
软骨肉瘤
头颈部
Chondrosarcoma
Head and neck
