摘要
目的探讨老年(≥80岁)心衰患者检测血管紧张素Ⅱ(AngⅡ)和肿瘤坏死因子(TNF)的临床意义。方法对30例住院心衰患者空腹抽血8ml,均采取低温离心,分离血浆置-20℃冰箱内储存并用放免法进行检测。结果对照组AngⅡ(42.80±21.09)ng/L,TNF(0.54±0.26)ng/L,老年心衰组AngⅡ(79.78±44.63)ng/L,TNF(1.97±0.36)ng/L明显高于对照组(P<0.01),心力衰竭严重程度与AngⅡ,TNF水平相关,心功能愈差,AngⅡ、TNF愈高。各组间比较差异显著。结论 AngⅡ、TNF与老年心衰发生和发展密切相关。
Objective To investigate the clinical singnificance of angiotensin Ⅱ（AngⅡ）and tumor necrosis factor（TNF）in elderly patitents with congestive heart failure（CHF）.Methods The levels of AngⅡ and TNF were determined in 30 patients by radioimmunoassay and the data were compared with those in normal control group.Results In old elderly heart failure group,The levels of AngⅡ and TNF were higher than those in normal control group（P0.01）.The plasma levels of AngⅡ and TNF were closely related with the degree of congestive heart failure.Conclusions AngⅡ and TNF were closely related with the development and progress of congestive heart failure in the elderly.
出处
《实用老年医学》
CAS
2010年第6期496-497,共2页
Practical Geriatrics
