燕麦配合调肝理脾通腑中药治疗便秘型肠易激综合征临床研究

Investigation of irritable bowel syndrome with constipation treated by combination of oats and Chinese medicine with liver spleen regulating fu-unblocking therapy

目的观察燕麦配合调肝理脾通腑中药治疗便秘型肠易激综合征(IBS)的临床疗效。方法将100例便秘型IBS患者随机分为2组。治疗组50例予燕麦配合调肝理脾通腑中药治疗,对照组50例予聚乙二醇4000治疗,2组均治疗1个月。观察2组临床疗效、单项症状改善率,统计中医症状积分。结果 2组痊愈率、总有效率比较差异均有统计学意义(P<0.05),治疗组疗效优于对照组。治疗组治疗后腹痛、排便形状异常、排便通过异常、黏液便、排便时腹胀或胃胀单项症状改善率均高于对照组(P<0.05)。2组治疗后中医症状积分均较本组治疗前降低(P<0.05),治疗组治疗后中医症状积分低于对照组(P<0.05)。结论燕麦配合调肝理脾通腑中药治疗便秘型IBS,可明显改善IBS患者的临床症状,疗效优于西药治疗,且使用方便,利于临床推广。

Objective To investigate irritable bowel syndrome with constipation treated by combination of oats and Chinese medicine with liver spleen regulating fu-unblocking therapy.Methods 100 cases of irritable bowel syndrome（IBS） with constipation were randomly divided into two groups.50 patients in treatment group were treated by combination of oats and Chinese medicine with liver spleen regulating fu-unblocking therapy.Patients in control group（n=50） were treated by polyethylene glycol 4000.The course was a month in two groups.The clinical effect,improvement rate of single symptom and traditional Chinese medicine symptoms score were observed.Results The cure rate and total effective rate in treatment group were superior to those in control group（P〈0.05）.The improvement rate of single symptom including stomachache,defecation shape abnormality,mucous stool,abdominal distention and gastric distention when defecation in treatment group was higher than that in control group（P〈0.05）.The traditional Chinese medicine symptoms score in treatment group was lower than that in control group after treatment（P〈0.05）.Conclusion Combination of oats and Chinese medicine with liver spleen regulating fu-unblocking therapy can improve clinical symptoms of patient of IBS with constipation.The effect was superior to that in control group.