急性胰腺炎细胞免疫功能测定

Determination of cellular immunity function in patients with acute pancreatitis

目的 探讨急性胰腺炎（ＡＰ） 病人的细胞免疫状态。方法 对３７ 例急性胰腺炎患者和１０ 例健康成人的Ｔ 淋巴细胞亚群，Ｃ 反应蛋白（ＣＲＰ） 进行测定分析。结果 Ｔ淋巴细胞亚群中ＣＤ４ 阳性细胞百分比和ＣＤ４／ＣＤ８ 比值在重症急性胰腺炎（ＳＡＰ） 患者中下降明显。结论 ＡＰ 患者特别是ＳＡＰ 患者存在细胞免疫功能损害，免疫调节治疗可能对ＳＡＰ 患者有一定的作用。邱新光， 男，３６ 岁， 医学博士， 河南医科大学附一院外科，４５００５２ 河南省郑州市建设东路１ 号秦兆寅，纪宗正， 黎一鸣， 西安医科大学第二附属医院外科，７１０００４ 陕西省西安市西五路３６

Objective To investigate the cellular immunity function in patients with acute pancreatitis (AP). Methods Determination of CD3, CD4, CD8 and CRP was made in 37 patients with severe acute pancreatitis (SAP) and 10 healthy adults separately. Results CD4 positive cell and CD4/CD8 ratio sharphy reduced is SAP patients. CRP were increased more than that in the mild pancreatitis. Conclusions Damage to cellular immunity function occurs in patients with AP, especially with SAP, so adjustable immutherapy may bring some effect on SAP.