低热量PN联合rhGH在严重腹腔感染病人的应用

The nutritional support for the patient with serious abdominal infection

目的：探讨低热量肠外营养（ＰＮ）和重组人生长激素（ｒｈＧＨ）联合应用对严重腹腔感染病人的作用。 方法：我院从１９９６ 年８ 月至１９９８年１２ 月，对４０ 例严重腹腔感染伴低蛋白血症的病人，采用低热量ＰＮ，配合短程小剂量ｒｈＧＨ 进行营养治疗，监测体重、血清白蛋白（Ａｌｂ）、转铁蛋白（ＴＦＮ）、肌酐身高指数、总淋巴细胞计数（ＴＬＣ）和计算氮平衡，并进行治疗前、后自身对照观察。 结果：治疗后血浆蛋白水平显著高于治疗前（Ｐ＜ ０．０５），差异显著。 结论：低热量ＰＮ与ｒｈＧＨ 联合应用，能够有效地克服严重腹腔感染病人所出现的营养代谢障碍，从而提高营养治疗的临床效果。

Objectives:To evaluate the clinical effects of Hypocaloric parenteral nutrition(HPN) and recombinant human growth hormone(rhGH) on the patient with serious abdominal infection. Methods:HPN and low dose rhGH(saizen) were given to 40 patients with serious adbominal infection and hypoalbuminosis,their weight,serum albumin,transferrin(TFN),creatinine height index(CHI),total lymphocyte count (TLC) and nitrogen balance were examined. Results:The protein increased significantly( P<0.05 ),self contrast prior to and after the test. Conclusions:The catabolic response of serious abdominal infection can be modified with GH and hypocaloric nutrition,it can improve the protein synthesis and nitrogen balance in short time,increase the clinical effects of nutritional treatment.