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肠康胶囊有关药理作用的实验研究 被引量:1

Experimental Study of Changkang Capsule on Pharmacological Actions
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摘要 目的:研究肠康胶囊的抑菌、行气、镇痛作用。方法:以肠康片作对照,体外抑菌试验用液体试管法,其余均用小鼠灌胃法,给1.04、0.52、0.26 3 种不同剂量。结果:肠康胶囊对大肠埃希氏菌等4 种肠道致病菌均有不同程度的抑制作用, 能对抗苦寒药大黄的致泻作用, 对新斯的明引起的小鼠推进运动亢进有明显的抑制作用,并具有明显的镇痛作用。结论:肠康胶囊的药理作用与肠康片相当甚至强于肠康片,为中药剂型的改进及临床验证提供了实验依据。 Objects: To research Changkang capsule's actions as bacteriostasis、promoting the circulation of Qi、easing pain. Methods: Compared with Changkang tablets, bacteriostatic test in vitro uses test-tube method ;others , all use rats with intragaster, giving three kinds of dosage: 1.04、0. 52、0. 26. Results:Changkang capsule has various degrees of inhibition on four kinds of enteric pathogenic bacteria, such as scherichia coli and so on, and has a distinct inhibition on lapactic action of Radix et Rhizomea Rhei, and has a inhibition on the rats with hyperfucal propulsive motion that induced by neostigmine, in addition, it has evidently analgesia action. Conclusions: Changkang capsule's pharmacological actions are equal to that of Changkang tablet, even better than that of Changkang tablet. It provides experimental evidence for improvement and clinical verify of Chinese drugs' form.
出处 《湖南中医药导报》 1999年第9期34-36,共3页 Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology
关键词 肠康胶囊 药理 肠康片 Changkang capsule Pharmacological actions Experiment Changkang tablet
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参考文献2

  • 1徐叔云.药理实验方法学[M].北京:人民卫生出版社,1994.713-723.
  • 2中华人民共和国卫生部药政管理局.中药新药研究指南[M].,1994.98.

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