摘要
目的:观察益欣康泰胶囊对小鼠缺氧耐受力的影响;方法:选用昆明种小鼠50只,随机分为对照组、阳性对照组和益欣康泰胶囊高、中、低剂量组,每组10 只。观察灌服益欣康泰胶囊溶液对实验性小鼠缺氧耐受力作用的影响;结果:给小鼠灌服150g/kg、10.0g/kg、5.0g/kg 体重的益欣康泰胶囊溶液及50g/kg 体重的红参醇提液后,均能明显延长小鼠的存活时间,其中益欣康泰胶囊作用优于红参组,其延长小鼠存活时间的作用与给药剂量呈正相关;结论:该药能明显提高小鼠的缺氧耐力。
To study effects of Yixinkangtai capsule on hypoxic tolerance of rats acute exposed to hypoxia.Methods:Kunming rats were divided into normal control group,taking equivalent distilled water by gastric perfusion;Positive group,taking 5.0g/kg of Jin sheng liquid;taking higher,moderate and lower dosage of Yixinkangtai group(15.0g/kg,10.0g/kg and 5.0g/kg).Results:The Yixinkangtai group and Jin sheng groug could prolong the surviraltime of hypoxic rats,specially in higer dosage of Yixinkangtai.Conclusions:Yixinkangtai capsule could increase the hypoxic tolerance of rats acute exposed to hyboxia.$$$$
出处
《高原医学杂志》
CAS
1999年第2期21-22,共2页
Journal of High Altitude Medicine