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益欣康泰胶囊对小鼠游泳耐力的影响 被引量:3

EFFECT OF YIXINKANGTAI ON TOLERANCE OF SWIMMING IN RATS
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摘要 目的:为了观察益欣康泰对小鼠游泳耐力的影响,以便提供临床用药;方法:选用健康昆明种小鼠75 只,按体重性别随机分成5 组,每组15 只,对照组灌服等体积蒸馏水;阳性对照组给以50g/kg 体重的优质红参醇提液;实验组灌服益欣康泰胶囊高、中、低剂量(15g、10g、5g/kg 体重),分别相当于成人拟服剂量的70 倍、47 倍、25 倍。各组动物于空吸12 小时后灌服给药50 分钟后开始实验。结果:该药可提高小鼠游泳耐力,延长游泳时间(P< 001);结论:提示该药具有增强小鼠体力、提高机体应激能力和抗疲劳作用。 To observ the effect of Yixinkangtai on tolerance of swimming in rats to provide the data for clinical treatment.Methods:75 rats of Kongming type were divide into 5 groups(10 for each)including one positive,one negative control group and three experimental groups according to their weights Distilled water was given to the negative control group,extrac of Hongsheng 5 0g/kg to positive control group,and Yixinkangtai of different dosages(low,middle and high)to experimental groups.Results:Our results showed that all three dosages could improve the tolerance of swimming in rats,and prolong the period of swimming ( P <0 01).Conclusions:This indicated that these can strengthen physical powre,and has ability of antifatigue.Authors preliminarily discussed the mechanism of the drug in this paper.$$$$
机构地区 青海省人民医院
出处 《高原医学杂志》 CAS 1999年第2期34-36,共3页 Journal of High Altitude Medicine
关键词 益欣康泰胶囊 游泳耐力 药理学 Yixinkangtai Tolerance Antigatigue Swiim.
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