IL-4与IL-6在急性脑梗死患者血清中的表达及临床意义

Detection of Serum IL-4 and IL-6 Cytokinesin Patients with Acute Cerebral Infrction and Its Clinical Significance

目的:观测急性脑梗死患者血清中IL-4和IL-6水平的变化,探讨其临床意义。方法:采用ELISA法测定28例急性脑梗死病人和36例正常人血清中IL-4和IL-6水细胞因子含量。结果:急性脑梗死病人血清中IL-4和IL-6水平分别为45.0±12.6和48.4±18.2,较正常对照组明显增高(P(0.01)。结论:急性脑梗死病人机体免疫功能紊乱,血清中IL-4和IL-6水平的变化可能与疾病的发生、发展有关系。

Objective：To investing the change of interleukin-4（IL-4）and interleukin-6（IL-6）levels in the serum of patients with acute cerebral infarction and clinical meaning.Methods：Levels of serusm IL-4 and IL-6 in 28 cases of cerebral infarction were detected by ELISA,and the data were compared and analyed with normal control.Results：Serum IL-4 and IL-6 levels were 45.0±12.6 and 48.4±18.2,respectly.Compared with the control group,it increased significantly（P﹤0.01）.Conclusion：It suggested that immune dysfunction exist in the patients with gastric carcinoma,higher levels of serum IL-4 and IL-6 would associated with genesis and development of the disease.