被动吸烟与儿童哮喘

Passive smoking and childhood asthma

被动吸烟对于儿童哮喘的发生及发展进程有着极大的负面影响.被动吸烟可导致发生儿童哮喘的风险上升.对于已经发展为哮喘的儿童,被动吸烟会影响哮喘控制,包括加重现有哮喘症状,诱发哮喘发作,降低生活质量,影响药物治疗.被动吸烟影响儿童哮喘发生及发展的机制还在进一步探索中,目前提出的相关机制主要有免疫功能异常、肺功能损害、气道高反应性及基因易患性.

Passive smoking causes significant adverse effects on the origins and progress of childhood asthma. Passive smoking may lead to an increased risk for the development of new cases of asthma in child. For the children who have already established asthma, passive smoking has great impact on asthma control, including increasing asthma symptoms, inducing exacerbations, decreasing quality of life and responsiveness to therapy drugs. The related mechanisms by which passive smoking makes induction of asthma and worsening of established asthma are still in exploration. The presented mechanisms have been postulated are impaired immune responses,impaired lung development, bronchial hyperreactivity, and genetic predisposition.