我国东北地区神经内科门诊患者认知功能调查及分析

Survey and analysis of cognitive function of outpatients in neurology clinic in Chinese Northeast region

目的调查东北地区神经内科门诊患者认知功能情况。方法选取2009年9月~12月吉林大学白求恩第一医院神经内科门诊就诊患者21849例,按照条件依次进行简易精神状态检查表（MMSE）及一系列神经心理评估。结果轻度认知功能障碍（MCI）占0.40%,其中轻度认知功能障碍-AD型（MCI-A）占0.12%,轻度认知功能障碍-血管型（MCI-V）占0.15%,混合性MCI占0.03%。痴呆患者占0.22%,其中阿尔茨海默病（AD）占0.06%,血管病性痴呆（VD）占0.11%,混合性痴呆（MD）占0.02%。其他占0.17%。男性MCI检出率为0.27%,痴呆检出率为0.22%。女性患者MCI检出率为0.33%,痴呆检出率为0.17%。结论东北地区血管性认知功能障碍发病率大于老年性认知功能障碍,女性轻度认知功能障碍检出率大于男性,而痴呆检出率小于男性,痴呆检出率随年龄增长成上升趋势,轻度认知功能障碍患者检出率在75岁之前随年龄增加明显升高,75岁前后比较检出率反而下降。

Objective To investigate the cognitive function in neurology clinic in Chinese Northeast region. Meth- ods The outpatients who satisfied our limited standard were selected in neurology clinic in the First Hospital of Jilin Uni- versity from September to November in 2009, and were conducted Mini-Mental State Examination （MMSE）and a series of neurologic psychological assessment. Results The patients classified as mild cognitive impairment （MCI）were 0.40% of the screened patients,and amomg them MCI-A were 0.12% ,MCI-V were 0.15% ,mixing MCI were 0.03%. The patients classified as dementia were 0.22% ,and among them the Alzheimer＇ s disease（AD） were 0.06% , vascular dementia（VD） were 0.11% ,the mixing dementia were 0.02%. In males,the detection rate of MCI was 0.27% ,the detection rate of de- mentia was 0.22%. In females,the detection rate of MCI was 0.33% ,the detection rate of dementia was 0.17%. Conclu- sion The incidence of MCI-V and VD surpass the incidence of MCI-A and AD in Chinese Northeast region. The detection rate of MCI of females is higher than that of males,but the detection rate of dementia is opposite. The detection rate of dementia increases gradually with age. The detection rate of MCI increases obviously before seventy-five years old,in patients above seventy-five years old, decreases obviously compared to the others.