焦虑症患者卧立位脑血流调节研究初探

Elementary study about the supine-standing cerebral blood flowin patients with anxiety

目的通过研究焦虑症患者卧立位脑血流调节趋势,探讨焦虑症患者神经系统症状与脑血流调节之间的关系。方法应用TCD检测10例焦虑症患者卧位与立位脑血流的变化,并通过脑血流曲线观察其变化特点。结果本组焦虑症患者中有7例由卧位转为立位时,脑血流在2min内未恢复到正常水平,其中5例患者脑血流下降幅度在11－20cm/s,2例患者脑血流下降幅度在21－39cm/s。结论部分焦虑症患者自主神经调节功能及脑血流自动调节能力显著下降,焦虑症患者神经系统症状的发生及较高的脑血管病患病率可能与此有关。

Objective To explore the relationship between neurological symptoms and cerebral blood flow autoregulation in patients with anxiety. Methods The supine-standing cerebral blood flow curves of middle cerebral artery were an- alyzed in 10 patients with anxiety using TCD. Results The cerebral blood flow（CBF） significantly decrease in 7 patients following standing up in 2minutes （5 patients 11 -20cm/s,2 patients 21 -39cm/s）. Conclusion The autonomic？ function and cerebral blood flow autoregulation of some anxiety disoder patients were decrease and these may lead to neurological symptoms as well as the cerebrovascular disease.