辽东楤木叶中一个新三萜皂苷(英文)

A New Triterpenoid Saponin from the Leaves of Aralia elata

目的:研究辽东木叶的化学成分。方法:采用硅胶、ODS、Sephadex LH-20等多种层析柱分离手段, 运用NMR和 HR-ESI-MS等波谱技术鉴定化合物的结构。结果:从辽东木叶分离并鉴定了1个三萜皂苷和2个黄酮苷类化合物:3-O-β-D-glucopyranosyl(1-3)-β-D-glucuronopyranoside-6'-O-butyl ester (1),7-O-α-rhamnopyranosyl-(S)-quercetin-3-O-β-glucopyra-nosyl-(1→2)-α-rhamnopyranoside(2)和7-O-α-rhamnopyranosyl-(S)-quercetin-3-O-β-6-caffeoyl-glucopyranosyl-(1→2)-α-rhamnopy-ranoside(3)。结论:化合物1为新化合物,也是从该属中分离出的第一个具有正丁基取代的三萜皂苷,化合物2和3为首次从该植物中分离得到。

AIM：To study the chemical constituents of the leaves of Aralia elata （Miq.） Seem,and find new or effective components.METHODS：Compounds were isolated by repeated silica gel,ODS and Sephadex LH-20 column chromatography.The structures were elucidated by NMR and HRESI-MS spectrometry.RESULTS：A triterpenoid saponin and two flavonoid glycosides were isolated from the leaves of A.elata,and their structures were elucidated as echinocystic acid-3-O-β-D-glucopyranosyl-（1-3）β-D-glucuronopyranoside-6＇-O-butyl ester （1）,7-O-α-rhamnopyranosyl-（S）-quercetin-3-O-β-glucopyranosyl-（1→2）-α-rhamnopyranoside （2） and 7-O-α-rhamnopyranosyl-（S）-quercetin-3-O-β-6-caffeoyl-glucopyranosyl-（1→2）-α-rhamnopyranos-ide （3）,respectively.CONCLUSION：Compound 1 is a new triterpenoid saponin,which is the first one with a butyl group isolated from the genus Aralia,while compounds 2 and 3 are reported from this species for the first time.