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Application of N-thiocyanatosuccinimide as a reagent for the facile conversion of epoxides into thiocyanohydrines

Application of N-thiocyanatosuccinimide as a reagent for the facile conversion of epoxides into thiocyanohydrines
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摘要 The use of in situ generated N-thiocyanatosuccinimide with NH4SCN offers an efficient reagent system for the conversion of epoxides into their corresponding thiocyanohydrines in good to high yields. The major advantages of this method are as follows: use of cheap reagent, high regioselectivity, simple availability of reagent, ease of workup of the reaction. The use of in situ generated N-thiocyanatosuccinimide with NH4SCN offers an efficient reagent system for the conversion of epoxides into their corresponding thiocyanohydrines in good to high yields. The major advantages of this method are as follows: use of cheap reagent, high regioselectivity, simple availability of reagent, ease of workup of the reaction.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2011年第1期21-24,共4页 中国化学快报(英文版)
基金 Shahid Chamran University of Ahvaz for financial support of this investigation
关键词 N-Thiocyanatosuccinimide Ring opening EPOXIDE Thiocyanohydrin N-Thiocyanatosuccinimide Ring opening Epoxide Thiocyanohydrin
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