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A facile and efficient method for hydroxylation of azabenzanthrone compounds

A facile and efficient method for hydroxylation of azabenzanthrone compounds
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摘要 A novel and facile method of introducing 4-hydroxyl group into the aromatic ring of azabenzanthrone compounds was carried out by reacting azabenzanthrone compounds with hydrazine hydrate or hydroxylamine hydrochloride and sodium hydroxide in diethylene glycol (DEG) solvent. The mechanism of reaction may involve an amino intermediate and follow a hydroxyl substitution process. A novel and facile method of introducing 4-hydroxyl group into the aromatic ring of azabenzanthrone compounds was carried out by reacting azabenzanthrone compounds with hydrazine hydrate or hydroxylamine hydrochloride and sodium hydroxide in diethylene glycol (DEG) solvent. The mechanism of reaction may involve an amino intermediate and follow a hydroxyl substitution process.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2011年第1期41-44,共4页 中国化学快报(英文版)
基金 the National Natural Science Foundation of China(No.30701050,20772159) the NSFC/RGC Joimt Research Scheme(No.3073060006)for financial support for this study
关键词 Azabenzanthrone HYDROXYLATION Hydrazine hydrate Hydroxylamine hydrochloride Sodium hydroxide Azabenzanthrone Hydroxylation Hydrazine hydrate Hydroxylamine hydrochloride Sodium hydroxide
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  • 1J. Kunitomo, M. Satoh, Chem. Pharm. Bull. 30 (1982) 2659.
  • 2H. Guinaudeau, J. Nat. Prod. 57 (1994) 1033.
  • 3J. Kunitomo, M. Satoh, T. Shingu, Tetrahedron 39 (1983) 3261.
  • 4S. Hu, S. Xu, X. Yao, et al. Chem. Pharm. Bull. 41 (1993) 1866.
  • 5M. Takani, Y. Takasu, K. Takahashi, Chem. Pharm. Bull. 31 (1983) 3091.
  • 6B.W. Yu, L.H. Meng, J.Y. Chert, et al. J. Nat. Prod. 64 (2001) 968.
  • 7C.F. Chen, Zhonghua Yaoxue Zazhi 44 (1992) 381.
  • 8H. Tang, EX. Ning, Y.B. Wei, et al. Bioorg. Med. Chem. Lett. 17 (2007) 3765.
  • 9S. Iwashima, T. Ueda, H. Honda, et al. J. Chem. Soc. Perkin Trans. 1 (1984) 2177.
  • 10J.J. Ritter, EO. Ritter, J. Am. Chem. Soc. 52 (1930) 2815.

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