灸法治疗维持性血液透析患者虚证:随机对照研究

Randomized controlled trail on moxibustion for maintenance hemodialysis patients in deficiency syndrome

目的:探寻治疗终末期肾脏病维持性血液透析患者虚证的有效疗法。方法:将97例终末期肾脏病维持性血液透析患者随机分为观察组(51例)、对照组(46例),两组均采用西医常规治疗方法;观察组在此基础上给予纸管贴穴灸疗器艾灸足三里、三阴交两穴。比较两组治疗前后症状积分,进行证候疗效评价。结果:观察组治疗后全部症状积分均有改善,差异有统计学意义(均P<0.05),尤以倦怠乏力、气短懒言、食少纳呆、腰膝酸软、畏寒肢冷等症状改善最为明显;证候疗效方面观察组总有效率64.7%(33/51),优于对照组的23.9%(11/46)(P<0.05)。结论:灸法能够改善终末期肾脏病维持性血液透析患者临床症状,对该类患者的虚证有一定的治疗作用。

Objective To explore the effective therapy for maintenance hemodialysis patients in dificiency syndrome in end-stage renal disease. Methods Ninety-seven cases were divided into an observation group （51 cases） and a control group （46 cases） randomly, and routine western medicine was used in both of them. On this base, moxibustion was used in Zusanli （ST 36） and Sanyinjiao （SP 6） in paper-tube-moxibustion equipment in the observation group. Evaluate the therapeutic effect on symptoms by comparing the symptom scores in two groups before and after treatment. Results All the symptom scores in the observation group were improved after treatment, and the differences were significant （all P〈0. 05）. Among all symptoms, the most improved ones included lassitude and fatigue, short breath and aversion to talk, poor appetite, soreness and softness of waist and knees, aversion to cold, cold extremities and so on. In the aspect of therapeutic effect on symptoms, the total effective rate in observation group （64.7%, 33/51） was higher than that in control group （23.9%, 11/46） , and the difference was significant （P〈0.05）. Conclusion Moxibustion can improve the clinical symptoms of maintenance hemodialysis patients in end-stage renal disease, and can generate some therapeutic effect to the dificiency syndrome of this disease.