1，2-二氯乙烷慢性中毒性脑病的磁共振成像分析

MRI image analysis of 1,2-dichloroethane chronic toxic encephalopath

目的回顾分析10例1，2-二氯乙烷（I，2-DCE）慢性中毒性脑病的磁共振成像（MRI）影像学特征。方法采用MRI对头部进行扫描，层厚8mm，层距2mm，行轴位及冠状位扫描，T1WI，T2WI，FLAIR成像。结果10例病例脑白质均表现不同程度异常信号，T1WI低信号，T2WI高信号，FLAIR高信号。临床中毒表现为轻、中度时，MRI表现为广泛的脑自质异常信号、呈现症状与表现不一致。结论1，2-DCE中毒性脑病均表现为脑白质不同程度信号改变，结合职业接触史具有特征性。

Objective To study the MRI features of 1,2-dichloroethane Chronic Toxic Encephalopathy of 10 cases. Method 10 cases were examined hy MRI, slice thieknegs gmm. layer from 2mm, axial and coronal line scan, T1WI, T2WI, FLAIR imaging. Results 10 cases show varying degrees of ahnormal signal of white matters,low signal intensity on T1WI, high signal intensity on T2WI and FLAIR. MRI eould also show extensive abnormal signal in cerebral white matter although the toxic manifestation is mild to moderate. There- fore the syptoms and the shows of MRI could be inconsistent. Conclusion Combined with a history of expo- sure, the show of varying degrees of abnormal signal of white matter in 1,2-dichloroethane Chronic Toxic Encephalopathy eases are characteristic.