不同睡眠期的阻塞性睡眠呼吸暂停低通气综合征严重程度

The severity of obstructive sleep apnea and hypopnea syndrome in different sleep stage

目的:普遍认为阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者快动眼睡眠期(REM)病情严重程度要比慢动眼睡眠期(NREM)重,通过对OSAHS患者REM期和NREM期临床及睡眠监测指标的比较分析,探讨不同睡眠期对OSAHS病情严重程度的影响。方法:回顾进行睡眠监测并诊断为OSAHS的118例患者,比较REM期睡眠呼吸暂停低通气指数(AHIREM)和NREM期AHI(AHINREM)的差别。并根据AHIREM和AHINREM将其分为2组:一组为AHIREM≥AHINREM组,另一组为AHIREM<AHINREM组。比较2组在性别、年龄、体质指数(BMI)、病情严重程度、最低血氧饱和度(Min SaO2)及平均呼吸暂停时间的差别。结果:AHIREM和AHINREM比较差异无统计学意义(t=1.0,P≥0.05);AHIREM/AHINREM为1.0±0.5;118例OSAHS患者中,AHIREM<AHINREM组占55.9%;2组在性别、年龄、BMI、AHI、仰卧位时AHI(AHIsupine)、Min SaO2和平均呼吸暂停时间比较差异均无统计学意义。结论:不同睡眠期的OSAHS病情严重程度差异无统计学意义。

Objective：This study aimed to inspect the hypothesis that obstructive sleep apnea and hypopnea syndrome（OSAHS） was commonly worse in REM sleep than in NREM sleep stage,and also to analyze the relevances with the risk factors of OSAHS.Method：One hundred eighteen patients diagnosed as OSAHS by overnight polysomnography（PSG） were studied retrospectively.The severity of OSAHS in REM versus NREM sleep was compared.Then the patients were divided into two groups：AHIREM≥AHINREM group,and AHIREMAHINREM group,and the two groups were compared in age,sex,BMI,AHI,AHI supine,oxygen desaturation and duration of apnea.Result： There was no significant difference between AHIREM and AHINREM.AHIREM/AHINREM was 1.0±0.5.A higher AHI NREM than AHI REM group was found in 55.9% of the 118 patients with OSAHS.There were no differences between the clinical and PSG foundings of two groups.Conclusion：The severity of OSAHS is not greatly influenced by sleep stage.