原发性小肠肿瘤51例临床分析

Clinical analysis on 51 cases of primary small intestine tumor

目的探讨原发性小肠肿瘤的临床特点和诊断手段。方法回顾性分析51例原发性小肠肿瘤患者的临床资料。结果 51例原发小肠肿瘤中,良性肿瘤6例(11.8%),恶性肿瘤45例(88.2%)。恶性肿瘤中术后病理类型为腺癌20例,淋巴瘤14例,间质瘤10例,类癌1例。临床表现无特异性,最常见症状是消化道出血。51例患者均经手术治疗,术前诊断率为47.1%。45例恶性肿瘤根治性切除率为46.7%(21/45),其中37例获随访患者中,22例已死亡,平均生存期(30±14)个月。结论小肠肿瘤临床表现不典型,早期诊断困难,对本病的警惕和认识有助于早期诊断和手术治疗。

Objective To explore the clinical characteristics and diagnosis of primary small intestine tumors. Methods We retrospectively analyzed the clinical data of 51 cases of primary small intestine tumor patients. Results Among 51 patients with primary small intestinal tumor,6 cases were benign tumor,while the other 45 cases were malignant tumor which includes 20 cases of adenocarcinomas,14 cases of lymphomas,10 cases of gastrointestinal stromal tumors（GIST） and 1 case of carcinoid.The clinical features were non-specific.The most common clinical manifestation was alimentary bleeding.All 51 cases underwent operation and the preoperative diagnostic rate was 47.1%.The radical resection rate in 45 malignant cases was 46.7%.In 37 follow-up cases,22 cases had already died and the average survival time was（30±14） months. Conclusions It is difficult to make an early diagnosis of primary small intestine tumor because of its atypical clinical manifestations.Physician＇s suspicion and awareness of the disease is crucial to the early diagnosis and surgical treatment.