期刊文献+

克罗恩病的影像学诊断 被引量:7

The Imaging Diagnosis Crohn’s Disease
原文传递
导出
摘要 目的探讨克罗恩病的影像学表现,以提高对该疾病的诊断认识。资料与方法回顾性分析36例克罗恩病患者的X线、CT、肠镜表现,观察病变累及的部位、范围、形态、并发症等特点。男23例,女13例,年龄16~58岁,平均(34.9±11.2)岁。所有病例均经病理证实。其中,回盲部病变15例,末端回肠10例,空肠3例,结肠(升、横、降结肠)6例,乙状结肠+直肠2例。结果 16例小肠+结肠气钡双重造影中,多节段性病变10例,多发性、纵行裂隙状溃疡8例,"卵石征"12例。12例腹部窦道造影中,肠瘘7例,腹腔脓肿形成6例,窦道形成4例。26例全腹部平扫+增强扫描中,肠壁增厚(>4mm)24例,强化较明显22例,肠管周围蜂窝织炎15例,腹腔内脓肿8例,系膜区淋巴结肿大(直径>5mm)9例,系膜区血管束增多、增粗7例,不全性肠梗阻11例,腹腔积液7例。24例消化内镜检查中,纵行裂隙状溃疡13例,"铺路石样卵石征"16例,肠腔不规则狭窄18例。结论克罗恩病的影像学表现有其特征性,可与其他肠道疾病相鉴别,能为临床诊断及治疗提供依据。 Objective To investigate the imaging features of Crohn’s disease,so as to improve the diagnosis.Materials and Methods The X ray,CT and enteroscope data of 36 patient (23 males and 13 females,ages ranged from 16 to 58 years,with a mean of 34.9±11.2 years) with Crohn’s disease were retrospectively analyzed.The imaging features including the position,appearance,extent,and complication of the Crohn’s disease were evaluated.Thirty six patients underwent X ray examination,26 underwent abdominal plain and enhacement CT scan,and 24 patients underwent enteroscope examination.Results Fifteen lesions located in ileocecal junction,10 in ileum,3 in jejunum,6 in colon,2 in sigmoid and rectum.On the double contrast barium enema images,10 cases showed segmented lesions,8 showed multiple longitudinal slit-shaped ulcers,12 showed pebble sign.On the fistulography images,7 cases had intestinal fistula,6 had peritoneal abscess,4 had sinus tract.On the abdominal plain and enhacement CT,24 cases showed bowel wall thickening(4mm),22 showed obviously enhanced,15 had dermatocellulitis,8 had peritoneal abscess,9 had lymphadenectasis(5mm),7 had vascular bundle thickening,11 had incomplete intestinal obstruction,7 had seroperitoneum.For the enteroscope findings,13 cases had longitudinal slit-shaped ulcers,16 had pebble sign,18 had irregular enteric carity stenosis.Conclusion The Crohn’s disease has characteristic imaging findings,which can help us in diagnosis.
出处 《临床放射学杂志》 CSCD 北大核心 2011年第1期62-65,共4页 Journal of Clinical Radiology
关键词 克罗恩病 X线 体层摄影术 X线计算机 肠镜 鉴别诊断 Crohn’s disease X-ray Tomography X-ray computed Enteroscope Differential diagnosis
  • 相关文献

参考文献2

二级参考文献50

  • 1[1]Ambrosini R,Barchiesi A,Di Mizio V,et al.Inflammatory chronic disease of the colon:how to image[J].Eur J Radiol,2007,61:442-448.
  • 2[2]Hanauer SB.Inflammatory bowel disease:epidemiology,pathogenesis,and therapeutic opportunities[J].Inflamm Bowel Dis,2006,12 (Suppl 1):S3-9.
  • 3[3]Kucharzik T,Maaser C,Lügering A,et al.Recent understanding of IBD pathogenesis:implications for future therapies[J].Inflamm Bowel Dis,2006,12:1068-1083.
  • 4[4]Hugot JP,Chamaillard M,Zouali H,et al.Association of NOD2 leucinerich repeat variants with susceptibility to Crohn's disease[J].Nature,2001,411:599-603.
  • 5[5]Ogura Y,Bonen DK,Inohara N,et al.A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease[J].Nature,2001,411:603-606.
  • 6[6]Rowe WA.Inflammatory bowel disease[J/OL].eMedicine,2004,7:1-43[2009-04-10].http://www.emedicine.com/MED/topic1169.htm.
  • 7[7]Bouma G,Strober W.The immunological and genetic basis of inflammatory bowel disease[J].Nat Rev Immunol,2003,3:521-533.
  • 8[8]Maul J,Loddenkemper C,Mundt P,et al.Peripheral and intestinal regulatory CD4+ CD25 (high) T cells in inflammatory bowel disease[J].Gastroenterology,2005,128:1868-1878.
  • 9[9]Present D,Rutgeerts P,Targun S,et al.Infliximab for the treatment of fistulas in patients with Crohn's disease[J].N Engl J Med,1999,340:1398-1405.
  • 10[10]Breese E,Michie C,Nicholls S,et al.Tumor necrosis factor alphaproducing cells in the intestinal mucasa of children with inflammatory bowel disease[J].Gastroenterology,1994,106:1455-1466.

共引文献40

同被引文献47

引证文献7

二级引证文献21

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部