抗凝、抗血小板及溶栓药物的合理应用

The rational application of the anticoagulative,antiplatelet and thrombolytic drugs

抗凝、抗血小板及溶栓药物是主要针对高危患者预防和治疗血栓形成、栓塞的一类药物,已广泛应用于血管成形和支架植入术。但抗凝、溶栓及抗血小板药物伴随一些不良反应,如出血、血小板减少症等。认识抗凝、溶栓及抗血小板药物的作用机制、适应证并加强监测,有助于我们合理、有效的选用药物,预防和减少不良反应和严重并发症的发生。

Anticoagulative,antiplatelet and thrombolytic drugs play an important role in preventing or treating thrombosis or embolism in some patients with high risk factors.These drugs have been extensively used in patients after angioplasty or stent implantation treatment.However,these drugs are associated with some side effects,such as bleeding,HIT,etc.It is necessary for physicians to recognize the mechanism and indications of these drugs,to closely monitor their side effects and complications,and to use these drugs appropriately and effectively.