老年患者医院血流感染危险因素的病例对照研究

Risk factors of hospital-acquired bloodstream infection in aged patients: a case-control study

目的探讨老年患者医院血流感染的危险因素。方法对老年医院血流感染患者采用1∶1配比的病例对照研究方法,采用多因素logistic回归分析。结果多因素logistic回归分析显示,有感染史(OR=14.075)、白蛋白<35 g/L(OR=4.155)、血糖>6.1 mmol/L(OR=3.459)、中性粒细胞<2.0×109/L(OR=7.417)、中心静脉置管≥14 d(OR=100.465)是老年患者医院血流感染发生的主要危险因素。结论应针对各种危险因素采取有效的预防措施,减少老年患者医院血流感染的发生。

OBJECTIVE To discuss the risk factors of hospital-acquired bloodstream infection in aged patients.METHODS A 1∶1 matched case-control study was designed.The available data were analyzed by a multiple Logistic regression analysis.RESULTS Multiple Logistic regression analysis showd that primary infectious focus（OR=14.075）,albumin35 g/L（OR=4.155）,plasma glucose11.1 mmol/l（OR=3.459）,neutrophil2.0 g/L（OR=7.417） and central venous catheterization in place for ≥14 days（OR=100.465） were important risk factors.CONCLUSION Effective measures should be taken to prevent hospital-acquired bloodstream infection in aged patients.