南昌社区中老年人群糖尿病流行病学调查中HbA1C对诊断2型糖尿病的价值

Value of HbA1C in the diagnosis of type 2 diabetes during an epidemiological survey of diabetes in the elderly of Nanchang community

选择南昌1 415例中老年人作为研究对象,分为正常糖耐量组、糖调节受损组及糖尿病组.结果 显示,HbA1C与空腹血糖（FPG）及餐后2 h血糖呈显著相关,HbA1C 6.3%诊断糖尿病的敏感度为85.19%,特异度为99.45%,HbA1C 6.5%诊断糖尿病的敏感度为75.56%,特异度为99.61%.在本研究的人群中,HbA1C 6.3%诊断糖尿病较HbA1C 6.5%及FPG 7.0 mmol/L具有更高的敏感性.

A total of1415 elderly individuals in Nanchang were included in the study and were divided into normal glucose tolerance group, impaired glucose regulation group, and diabetes mellitus group.The results showed that HbA1C was significantly correlated with fasting plasma glucose （FPG） and 2 h postprandial plasma glucose.When HbA1C 6.3% was applied as the cut point of diabetes, the sensitivity was 85.19% and the specifity was 99.45%.When HbA1C 6.5% was applied, the sensitivity was 75.56% and specifity was 99.61%.It seems that HbA1C 6.3% had higher specifity and sensitivity for diagnosing diabetes than HbA1C 6.5% and FPG 7.0mmol/L in studied population.